CTTI's organization comprises three components:
The Executive Committee sets the overall direction and strategy for the initiative.
The Steering Committee, consisting of representatives from CTTI’s approximately 80 member organizations, provides input into decisions about CTTI priorities, projects, and recommendations. CTTI members also play an important role in facilitating improvements in the design and conduct of clinical trials within their organizations and the overall ecosystem.
CTTI’s staff supports the development and execution of projects and communication of project results and impact. In addition, staff members organize and support the activities of the Executive and Steering Committees.