CTTI has announced new resources to facilitate the implementation of single IRB (sIRB) in multicenter trials. The tools walk research institutions, sponsors, and IRBs through considerations for determining engagement, and provide a library of available sIRB resources. They are enhancements to CTTI’s extensive work on the topic dating back to 2010, which was featured in a recent issue of Contemporary Clinical Trials Communications.
“For nearly a decade, CTTI has been at the forefront of the sIRB movement, championing the thoughtful implementation of sIRBs for multicenter clinical trials to enhance patient safety, accelerate study start-up, and improve trial conduct,” said Pamela Tenaerts, executive director of CTTI. “We are pleased to unveil new resources to address some of the most pressing sIRB challenges and information gaps that remain for researchers. These tools augment CTTI’s already robust set of resources to collectively make sIRB adoption more seamless for the clinical trials enterprise.”
CTTI’s new tools include:
More information on these new resources is available via a recent CTTI-hosted webinar that features Nichelle Cobb (University of Wisconsin-Madison) unveiling the tools and showcasing their utility. The webinar also includes an overview of CTTI’s previous and ongoing work on sIRB for multicenter clinical trials, as well as results of recent semi-structured interviews to assess current perceptions of sIRB benefits, process challenges and solutions, and informational needs for using an sIRB process for FDA-regulated studies.